The regulars in the last 16 such as Bayern Munich, Juventus and PSG passed their respective tests and Basel, Roma, Shakhtar Donetsk, Besiktas and Porto all continue on into the next round too.
The England international then forced Igor Akinfeev to keep out his 15th-minute effort while Lukaku's shot was blocked after the CSKA goalkeeper had saved Luke Shaw's volley. In the end, Roma's win against Qarabag made the result irrelevant for Diego Simeone's team, who failed to qualify for the last 16 for the first since the 2009-10 season. The Italian champions go through behind Barcelona, who rounded off their group phase by easing to a 2-0 win at home against Sporting Lisbon.Lionel Messi was left on the bench at a sparsely populated Camp Nou as Paco Alcacer headed the hosts in front and Jeremy Mathieu then scored an own goal against his old side.
As group winners, United can draw only the runners up of the other seven groups, while Chelsea can only face group winners and as you can see from the two tables below, both teams could be drawn against some of Europe's biggest heavyweights.
Atletico Madrid's Champions League exit will cost the club €30m and two players could be sold in January to make up for it.
The four teams to have secured second spot on Tuesday were Basel, Bayern Munich, Chelsea and Juventus.
These restrictions are removed ahead of the quarter-finals.
"No, Marcos is really tired", Mourinho told BT Sport before the CSKA Moscow match when asked if Rojo had another injury.
However, fine finishes from Romelu Lukaku and Rashford within seconds turned the scoreline on its head with 25 minutes remaining and Jose Mourinho's men coasted over the finishing line.
'I think it doesn't matter the team we get in the draw. Liverpool are among the sides hoping to secure a place in the last 16 on Wednesday, with four more berths still up for grabs.