The Portuguese international has yet to score in this season's league and with Benzema back in the side he will be hoping the partnership clicks again as Madrid look for their 13th consecutive game away from home.
Speaking in an interview with Cope, the Argentinian manager called on his team to be 'brave'.
The goalkeeper spent three years in the Spanish capital during his loan spell at Atletico Madrid from 2011-2014.
"It's obvious that we will use the weapons we have to try and play well and win, because we are going there to win". According to Mundo Deportivo the French tactician could decide to step down as the Merengues coach at the end of the season if France call him after the 2018 World Cup.
The final area of concern is defence and Real Sociedad right back Alvaro Odriozola is being targeted as a potential backup for Dani Carvajal.
"Zidane has the difficult task of trying to make happy hundreds of millions of supporters who are spread across the world and know that our team is in the best hands possible", he concludes.
Bale is currently nursing a calf issue while Benzema has a hamstring injury, joining Keylor Navas (Achilles), Marcelo (Thigh) and Mateo Kovacic (partial abductor tear) on the treatment table.